The latest update of WordPress – version 3.3. – is now out and it mainly features changes to the admin interface. This video gives you a quick tour of those changes.
As always, the question is: change over now or wait?
I always recommend waiting for at least a couple of weeks, in case an unknown issue crops up. WordPress is thoroughly tested, but as with any complex software, there are so many parameters it sometimes takes use by thousands and thousands of people for a bug to show up.